node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDY71110.1 | SDY88623.1 | SAMN05660462_00719 | SAMN05660462_01142 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formimidoyltetrahydrofolate cyclodeaminase. | 0.747 |
SDY71110.1 | fhs | SAMN05660462_00719 | SAMN05660462_01138 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.769 |
SDY71110.1 | fmt | SAMN05660462_00719 | SAMN05660462_01528 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.581 |
SDY71110.1 | folD | SAMN05660462_00719 | SAMN05660462_02215 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.889 |
SDY71110.1 | glyA | SAMN05660462_00719 | SAMN05660462_02075 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.400 |
SDY71110.1 | purH | SAMN05660462_00719 | SAMN05660462_02739 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.488 |
SDY71110.1 | purN | SAMN05660462_00719 | SAMN05660462_02738 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.775 |
SDY88623.1 | SDY71110.1 | SAMN05660462_01142 | SAMN05660462_00719 | Formimidoyltetrahydrofolate cyclodeaminase. | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. | 0.747 |
SDY88623.1 | fhs | SAMN05660462_01142 | SAMN05660462_01138 | Formimidoyltetrahydrofolate cyclodeaminase. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.948 |
SDY88623.1 | fmt | SAMN05660462_01142 | SAMN05660462_01528 | Formimidoyltetrahydrofolate cyclodeaminase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.827 |
SDY88623.1 | folD | SAMN05660462_01142 | SAMN05660462_02215 | Formimidoyltetrahydrofolate cyclodeaminase. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.973 |
SDY88623.1 | gcvT | SAMN05660462_01142 | SAMN05660462_00973 | Formimidoyltetrahydrofolate cyclodeaminase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.854 |
SDY88623.1 | glyA | SAMN05660462_01142 | SAMN05660462_02075 | Formimidoyltetrahydrofolate cyclodeaminase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.603 |
SDY88623.1 | purH | SAMN05660462_01142 | SAMN05660462_02739 | Formimidoyltetrahydrofolate cyclodeaminase. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.804 |
SDY88623.1 | purN | SAMN05660462_01142 | SAMN05660462_02738 | Formimidoyltetrahydrofolate cyclodeaminase. | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.812 |
SDZ33400.1 | fhs | SAMN05660462_02734 | SAMN05660462_01138 | Phosphoribosylformylglycinamidine synthase. | Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. | 0.984 |
SDZ33400.1 | fmt | SAMN05660462_02734 | SAMN05660462_01528 | Phosphoribosylformylglycinamidine synthase. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.930 |
SDZ33400.1 | folD | SAMN05660462_02734 | SAMN05660462_02215 | Phosphoribosylformylglycinamidine synthase. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.935 |
SDZ33400.1 | gcvT | SAMN05660462_02734 | SAMN05660462_00973 | Phosphoribosylformylglycinamidine synthase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.721 |
SDZ33400.1 | glyA | SAMN05660462_02734 | SAMN05660462_02075 | Phosphoribosylformylglycinamidine synthase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.996 |