STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABX21907.1Hypothetical protein; KEGG: spt:SPA1865 6.1e-164 ybjU; L-allo-threonine aldolase K01620; COG: COG2008 Threonine aldolase. (318 aa)    
Predicted Functional Partners:
gcvP
Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.961
glyA
Hypothetical protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.930
ABX22833.1
Hypothetical protein; KEGG: stm:STM0004 2.2e-221 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase.
   
 0.923
ilvA
Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.916
ABX24153.1
Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.915
ABX21345.1
Hypothetical protein; KEGG: sty:STY1550 5.0e-130 putative oxidoreductase; COG: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Psort location: Cytoplasmic, score:9.26; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.913
kbl
Hypothetical protein; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
     
 0.913
tdh
Hypothetical protein; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
     
 0.900
ABX21908.1
Hypothetical protein; KEGG: eci:UTI89_C0872 4.5e-216 ybjT; hypothetical protein YbjT K00329:K00356; COG: COG0702 Predicted nucleoside-diphosphate-sugar epimerases; Psort location: CytoplasmicMembrane, score:9.82.
  
    0.819
ychF
Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
      0.717
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.