STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABX22329.1Hypothetical protein; KEGG: ter:Tery_3993 1.1e-35 adenylate/guanylate cyclase K01769; COG: COG0004 Ammonia permease; Psort location: CytoplasmicMembrane, score:10.00. (428 aa)    
Predicted Functional Partners:
ABX22331.1
Hypothetical protein; KEGG: pmn:PMN2A_0116 0.0078 3-dehydroquinate synthase K01735; COG: COG0347 Nitrogen regulatory protein PII; Psort location: Cytoplasmic, score:8.96; Belongs to the P(II) protein family.
 
 0.999
ABX20254.1
COG: COG0347 Nitrogen regulatory protein PII; Psort location: Cytoplasmic, score:8.96; Belongs to the P(II) protein family.
 
 0.998
ABX24077.1
Hypothetical protein; KEGG: stt:t3247 0. gltB; glutamate synthase [NADPH] large chain precursor K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96.
 
  
 0.966
glnD
Hypothetical protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
 
   
 0.863
ABX23464.1
Hypothetical protein; KEGG: stm:STM4006 1.0e-177 glnL; sensory kinase (phosphatase) in two-component regulatory system with GlnG (nitrogen regulator II, NRII) K07708; COG: COG3852 Signal transduction histidine kinase, nitrogen specific; Psort location: CytoplasmicMembrane, score:9.82.
 
 
 0.782
ABX23463.1
Hypothetical protein; KEGG: sdy:SDY_3873 9.7e-253 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97.
  
  
 0.768
ABX22330.1
Hypothetical protein; Psort location: Cytoplasmic, score:8.96.
       0.568
cysG
Hypothetical protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.537
ntrC
Hypothetical protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
   
  
 0.527
ABX21152.1
Hypothetical protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.477
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.