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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsHypothetical protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa)    
Predicted Functional Partners:
ABX21234.1
Hypothetical protein; KEGG: spt:SPA1236 0. nifJ; probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
  
 0.988
ABX20488.1
Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.981
ackA
Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.965
ABX22089.1
Hypothetical protein; KEGG: sec:SC0736 5.1e-231 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
  
 0.958
ABX22413.1
Hypothetical protein; KEGG: stm:STM0369 9.4e-207 prpC; putative citrate synthase K01659; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.97.
  
 0.958
ABX23302.1
Hypothetical protein; KEGG: stm:STM4183 4.6e-285 aceB; malate synthase A K01638; COG: COG2225 Malate synthase; Psort location: Cytoplasmic, score:9.97.
   
 0.956
fadJ
Hypothetical protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.950
fadB
Hypothetical protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.950
ABX21106.1
Hypothetical protein; KEGG: stm:STM1749 0. adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.26; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.945
ABX20354.1
Hypothetical protein; KEGG: eci:UTI89_C2782 3.1e-153 eutD, ypfA, eutI; ethanolamine utilization protein EutD acetyl/butyryl phosphate transferase K04020; COG: COG0280 Phosphotransacetylase.
   
 
 0.938
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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