Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acsHypothetical protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa)    
Predicted Functional Partners:
ABX21234.1
Hypothetical protein; KEGG: spt:SPA1236 0. nifJ; probable pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
  
 0.988
ABX20488.1
Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.957
ackA
Hypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.955
ABX22089.1
Hypothetical protein; KEGG: sec:SC0736 5.1e-231 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
  
 0.934
ABX22413.1
Hypothetical protein; KEGG: stm:STM0369 9.4e-207 prpC; putative citrate synthase K01659; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.97.
  
 0.934
ABX23302.1
Hypothetical protein; KEGG: stm:STM4183 4.6e-285 aceB; malate synthase A K01638; COG: COG2225 Malate synthase; Psort location: Cytoplasmic, score:9.97.
   
 0.932
ABX20354.1
Hypothetical protein; KEGG: eci:UTI89_C2782 3.1e-153 eutD, ypfA, eutI; ethanolamine utilization protein EutD acetyl/butyryl phosphate transferase K04020; COG: COG0280 Phosphotransacetylase.
     
 0.927
leuA
Hypothetical protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.925
ABX24405.1
Hypothetical protein; KEGG: stt:t2929 9.3e-200 yqeF; probable acetyl-CoA acetyltransferase K00626; COG: COG0183 Acetyl-CoA acetyltransferase; Psort location: Cytoplasmic, score:9.97; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.925
ABX24355.1
Hypothetical protein; KEGG: ssn:SSO_3071 5.5e-234 ygfH; putative coenzyme A transferase K01041; COG: COG0427 Acetyl-CoA hydrolase; Psort location: Cytoplasmic, score:8.96.
  
 0.923
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.