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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABX23301.1Hypothetical protein; KEGG: spt:SPA4022 5.7e-232 aceA; isocitrate lyase K01637; COG: COG2224 Isocitrate lyase; Psort location: Cytoplasmic, score:9.97. (439 aa)    
Predicted Functional Partners:
ABX23302.1
Hypothetical protein; KEGG: stm:STM4183 4.6e-285 aceB; malate synthase A K01638; COG: COG2225 Malate synthase; Psort location: Cytoplasmic, score:9.97.
 
 0.999
aceK
Hypothetical protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
 
  
 0.990
ABX21152.1
Hypothetical protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.930
ABX22683.1
Hypothetical protein; KEGG: sty:STY0181 0. acnB; aconitate hydratase 2 (citrate hydro-lyase 2) K01682; COG: COG1049 Aconitase B; Psort location: Cytoplasmic, score:8.96; Belongs to the aconitase/IPM isomerase family.
     
 0.921
ghrA
Hypothetical protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
   
 
 0.911
ABX23787.1
Hypothetical protein; KEGG: sec:SC3578 5.5e-76 yiaE; 2-keto-D-gluconate reductase K00090; COG: COG1052 Lactate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.97.
     
 0.910
ABX20970.1
Hypothetical protein; KEGG: stm:STM1884 8.0e-107 eda; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase K01570:K01625:K01650; COG: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; Psort location: Cytoplasmic, score:9.97.
     
 0.907
ABX20488.1
Hypothetical protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.726
ABX22089.1
Hypothetical protein; KEGG: sec:SC0736 5.1e-231 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.26.
   
  
 0.686
ABX20347.1
Hypothetical protein; KEGG: sty:STY2709 0. maeB; NADP-dependent malate dehydrogenase (decarboxylating) K00029; COG: COG0280 Phosphotransacetylase.
   
  
 0.681
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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