Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABX23322.1COG: COG2104 Sulfur transfer protein involved in thiamine biosynthesis. (66 aa)    
Predicted Functional Partners:
ABX23321.1
Hypothetical protein; KEGG: eci:UTI89_C3827 2.2e-111 thiF; adenylyltransferase ThiF K03148; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
 0.999
thiG
Hypothetical protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.996
thiC
Hypothetical protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.986
thiE
Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.976
ABX23324.1
Hypothetical protein; KEGG: mac:MA0154 1.0e-11 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
 
    0.973
ABX20676.1
Hypothetical protein; KEGG: stm:STM2146 2.8e-136 thiD; bifunctional enzyme: hydroxy-phosphomethylpyrimidine kinase (HMP-P kinase); hydroxy-methylpyrimidine kinase (HMP kinase) K00877:K00941; COG: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
  
  
 0.866
ABX21955.1
Hypothetical protein; KEGG: eci:UTI89_C0829 1.4e-116 moeB; molybdopterin biosynthesis protein MoeB K03751; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2; Psort location: Cytoplasmic, score:8.96.
  
 
 0.768
ABX23185.1
Hypothetical protein; KEGG: ech:ECH_1107 3.6e-14 thiF; adenylyltransferase ThiF; COG: COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
 
 0.681
frdD
Hypothetical protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.
  
     0.578
ABX23493.1
Hypothetical protein; KEGG: yps:YPTB0915 0.00021 sbcC; putative ATP-dependent dsDNA exonuclease K03546; COG: COG1322 Uncharacterized protein conserved in bacteria.
      
 0.575
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.