STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
treFHypothetical protein; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity. (549 aa)    
Predicted Functional Partners:
ABX20920.1
Hypothetical protein; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
  
 0.978
ABX21308.1
Hypothetical protein; KEGG: sme:SMb21447 4.3e-147 glgB2; putative 1,4-alpha-glucan branching enzyme protein K00700; COG: COG0296 1,4-alpha-glucan branching enzyme; Psort location: Cytoplasmic, score:9.26.
  
 
 0.941
treA
Hypothetical protein; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.
  
  
 
0.905
otsA
Hypothetical protein; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
  
  
 0.607
ABX22046.1
Hypothetical protein; Converts alpha-aldose to the beta-anomer.
  
  
  0.558
ABX21551.1
Hypothetical protein; KEGG: sec:SC1339 1.3e-27 katE; catalase; hydroperoxidase HPII(III), RpoS dependent K03781; COG: COG0753 Catalase.
   
  
 0.557
glk
Hypothetical protein; KEGG: stm:STM2403 2.3e-171 glk; glucokinase K00845; COG: COG0837 Glucokinase; Psort location: Cytoplasmic, score:9.97; Belongs to the bacterial glucokinase family.
     
 0.505
ABX23457.1
Hypothetical protein; KEGG: eco:b3879 5.4e-85 yihR; predicted aldose-1-epimerase K01785; COG: COG2017 Galactose mutarotase and related enzymes.
     
  0.499
ABX22115.1
Hypothetical protein; KEGG: stt:t2177 7.6e-292 pgm; phosphoglucomutase K01835; COG: COG0033 Phosphoglucomutase.
  
  
 0.406
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.