STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nikRHypothetical protein; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel. (133 aa)    
Predicted Functional Partners:
rcnR
Hypothetical protein; Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter (By similarity); Belongs to the FrmR/RcnR family.
      
 0.819
ABX24299.1
Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system.
  
 
 0.809
birA
Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.578
ABX23846.1
Hypothetical protein; KEGG: sty:STY4228 4.2e-94 4'-phosphopantetheinyl transferase K06133; COG: COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
       0.541
ABX24005.1
Hypothetical protein; KEGG: eci:UTI89_C3737 1.2e-64 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: Cytoplasmic, score:8.96.
      
 0.491
ABX22296.1
Hypothetical protein; KEGG: eci:UTI89_C3737 8.2e-18 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG0789 Predicted transcriptional regulators; Psort location: Cytoplasmic, score:8.96.
      
 0.479
rcnA
Hypothetical protein; Efflux system for nickel and cobalt.
  
   
 0.471
ABX23847.1
Hypothetical protein; KEGG: tbd:Tbd_2668 4.3e-11 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:10.00.
       0.443
ABX21966.1
Hypothetical protein; COG: COG1321 Mn-dependent transcriptional regulator; Psort location: Cytoplasmic, score:8.96.
     
 0.400
Your Current Organism:
Salmonella enterica arizonae
NCBI taxonomy Id: 41514
Other names: S. enterica subsp. arizonae serovar 62:z4,z23:-, Salmonella enterica IIIa 62:z4,z23:-, Salmonella enterica serovar IIIa 62:z4,z23:-, Salmonella enterica subsp. arizonae serovar 62:z4,z23:-
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.