| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Hbut_0064 | Hbut_1281 | Hbut_0064 | Hbut_1281 | XPD/Rad3 related DNA helicase. | DNA or RNA helicases of superfamily II. | 0.969 |
| Hbut_0064 | Hbut_1573 | Hbut_0064 | Hbut_1573 | XPD/Rad3 related DNA helicase. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.913 |
| Hbut_0064 | rpoD | Hbut_0064 | Hbut_0530 | XPD/Rad3 related DNA helicase. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.900 |
| Hbut_0064 | rpoH | Hbut_0064 | Hbut_1572 | XPD/Rad3 related DNA helicase. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.900 |
| Hbut_0064 | rpoN | Hbut_0064 | Hbut_0534 | XPD/Rad3 related DNA helicase. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.899 |
| Hbut_0064 | rpoP | Hbut_0064 | Hbut_0052 | XPD/Rad3 related DNA helicase. | DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.900 |
| Hbut_0064 | tbp | Hbut_0064 | Hbut_0934 | XPD/Rad3 related DNA helicase. | TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.902 |
| Hbut_0064 | tfb | Hbut_0064 | Hbut_0054 | XPD/Rad3 related DNA helicase. | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.825 |
| Hbut_0064 | tfe | Hbut_0064 | Hbut_1136 | XPD/Rad3 related DNA helicase. | Predicted transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...] | 0.953 |
| Hbut_1135 | tfe | Hbut_1135 | Hbut_1136 | Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Predicted transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...] | 0.942 |
| Hbut_1281 | Hbut_0064 | Hbut_1281 | Hbut_0064 | DNA or RNA helicases of superfamily II. | XPD/Rad3 related DNA helicase. | 0.969 |
| Hbut_1281 | Hbut_1573 | Hbut_1281 | Hbut_1573 | DNA or RNA helicases of superfamily II. | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.935 |
| Hbut_1281 | rpoD | Hbut_1281 | Hbut_0530 | DNA or RNA helicases of superfamily II. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.945 |
| Hbut_1281 | rpoH | Hbut_1281 | Hbut_1572 | DNA or RNA helicases of superfamily II. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.952 |
| Hbut_1281 | rpoN | Hbut_1281 | Hbut_0534 | DNA or RNA helicases of superfamily II. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.929 |
| Hbut_1281 | rpoP | Hbut_1281 | Hbut_0052 | DNA or RNA helicases of superfamily II. | DNA-directed RNA polymerase, subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.928 |
| Hbut_1281 | tbp | Hbut_1281 | Hbut_0934 | DNA or RNA helicases of superfamily II. | TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.949 |
| Hbut_1281 | tfb | Hbut_1281 | Hbut_0054 | DNA or RNA helicases of superfamily II. | Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). | 0.836 |
| Hbut_1281 | tfe | Hbut_1281 | Hbut_1136 | DNA or RNA helicases of superfamily II. | Predicted transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and dest [...] | 0.967 |
| Hbut_1573 | Hbut_0064 | Hbut_1573 | Hbut_0064 | DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | XPD/Rad3 related DNA helicase. | 0.913 |
