STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCZ50201.1Hydrogenase maturation protease. (152 aa)    
Predicted Functional Partners:
SCZ59471.1
Sulfide:quinone oxidoreductase.
    
 
 0.708
SCZ59563.1
Sulfide-quinone oxidoreductase.
    
 
 0.708
SCZ59096.1
Coenzyme F420-reducing hydrogenase, gamma subunit.
  
 
 0.680
SCZ49123.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
     
 0.643
SCZ57433.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
     
 0.537
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
    
   0.512
SCZ50197.1
EF hand.
       0.503
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
   0.481
SCZ52341.1
Putative adenylylsulfate reductase-associated electron transfer protein QmoB.
  
  
 0.417
SCZ61063.1
Hydrogenase expression/formation protein HypC.
  
  
 0.414
Your Current Organism:
Thiohalomonas denitrificans
NCBI taxonomy Id: 415747
Other names: DSM 15841, T. denitrificans, Thiohalomonas denitrificans Sorokin et al. 2007, UNIQEM U222, halophilic bacterium HLD 1, halophilic bacterium HLD 16, strain HLD 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.