STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCZ52367.1Nitroreductase. (199 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.852
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.730
SCZ54768.1
Peroxiredoxin Q/BCP.
 
      0.658
SCZ64872.1
Acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase.
   
   0.467
SCZ62102.1
Cysteine desulfurase NifS; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
  0.459
SCZ66250.1
Glutamate synthase (NADPH/NADH) large chain.
     
 0.458
SCZ52372.1
Hypothetical protein.
       0.452
SCZ49123.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
  
 0.447
SCZ50067.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
   
   0.429
SCZ55983.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
   
   0.429
Your Current Organism:
Thiohalomonas denitrificans
NCBI taxonomy Id: 415747
Other names: DSM 15841, T. denitrificans, Thiohalomonas denitrificans Sorokin et al. 2007, UNIQEM U222, halophilic bacterium HLD 1, halophilic bacterium HLD 16, strain HLD 2
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