STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCZ61045.1Hydrogenase expression/formation protein HypE. (347 aa)    
Predicted Functional Partners:
SCZ61053.1
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
 0.997
SCZ61063.1
Hydrogenase expression/formation protein HypC.
 
 
 0.991
SCZ61069.1
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 0.984
SCZ50249.1
Hydrogenase nickel incorporation protein HypB.
 
  
 0.836
hypA
Hydrogenase nickel incorporation protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.818
SCZ57433.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
     
 0.675
SCZ49123.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
     
 0.618
SCZ61038.1
Putative two-component system protein, hydrogenase maturation factor HypX/HoxX.
  
    0.578
SCZ59090.1
Coenzyme F420-reducing hydrogenase, alpha subunit.
 
   
 0.549
Your Current Organism:
Thiohalomonas denitrificans
NCBI taxonomy Id: 415747
Other names: DSM 15841, T. denitrificans, Thiohalomonas denitrificans Sorokin et al. 2007, UNIQEM U222, halophilic bacterium HLD 1, halophilic bacterium HLD 16, strain HLD 2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.