Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
APL_0029ABC transporter periplasmic protein. (524 aa)    
Predicted Functional Partners:
APL_0027
Nickel transport system permease protein.
 
 0.992
APL_0028
ABC transporter permease protein.
 
  0.992
APL_0026
ABC transporter ATP-binding protein.
 
  0.987
APL_0849
Inner membrane ABC transporter permease.
 
  0.976
APL_0850
ABC transporter, ATP-binding/permease; Belongs to the binding-protein-dependent transport system permease family.
 
 0.948
APL_0851
ABC transporter, ATP-binding subunit.
 
  0.943
APL_0848
Putative ABC transporter periplasmic binding protein.
  
  
 
0.924
APL_1001
Putative binding protein.
 
 
0.910
dppC
Dipeptide transport system permease protein DppC.
 
 
 0.788
dppB
Dipeptide transport system permease protein DppB.
 
   0.773
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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