STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manBPhosphomannomutase. (452 aa)    
Predicted Functional Partners:
manA
Mannose-6-phosphate isomerase.
  
 
 0.914
galU
UTP--glucose-1-phosphate uridylyltransferase.
  
 0.911
APL_1391
PTS system mannose-specific EIIAB component; Includes: Mannose-specific phosphotransferase enzyme IIA component; Mannose-specific phosphotransferase enzyme IIB component.
    
 0.909
APL_1662
PTS system mannose-specific EIIAB component; Includes: Mannose-specific phosphotransferase enzyme IIA component; Mannose-specific phosphotransferase enzyme IIB component.
    
 0.909
pgm
Phosphoglucomutase/phosphomannomutase.
     
 0.906
ptnC
Mannose permease IIC component.
     
  0.900
ptnD
Mannose permease IID component.
     
  0.900
APL_1660
Mannose permease IID component.
     
  0.900
APL_1661
Mannose permease IIC component.
     
  0.900
csrA
Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
       0.675
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.