Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ushAUshA precursor; Includes: UDP-sugar hydrolase; 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (547 aa)    
Predicted Functional Partners:
udk
Uridine kinase.
  
 
  0.943
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
 
  
  0.933
APL_0132
Putative haloacid dehalogenase-like hydrolase.
  
 
 0.931
APL_1743
Ser/Thr protein phosphatase family protein; Belongs to the 5'-nucleotidase family.
  
 
0.931
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor; Belongs to the 5'-nucleotidase family.
  
 
0.930
surE
5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.927
tdk
Thymidine kinase.
 
  
  0.924
nadR
Transcriptional regulator NadR.
     
 0.914
APL_1072
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
  0.911
deoD
Purine nucleoside phosphorylase DeoD-like protein.
    
 0.908
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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