Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APL_0863Hypothetical protein; Belongs to the UPF0181 family. (54 aa)    
Predicted Functional Partners:
APL_0861
Hypothetical protein.
       0.790
truC
tRNA pseudouridine synthase C.
       0.790
fic
Filamentation induced by cAMP protein Fic-like protein.
       0.773
APL_0864
Hypothetical protein.
       0.773
trpCF
Tryptophan biosynthesis protein trpCF; Includes: Indole-3-glycerol phosphate synthase; N-(5'-phospho-ribosyl)anthranilate isomerase; Belongs to the TrpC family.
       0.508
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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