dapA protein (Actinobacillus pleuropneumoniae)

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dapA

Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)

Predicted Functional Partners:

dapB

0.987

thrA

0.967

asd

0.926

lysA

0.902

lysC

0.733

dapF

0.721

dapD

0.687

argD

0.632

APL_1222

0.630

pheA

0.577

Your Current Organism:

Actinobacillus pleuropneumoniae

NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APL_1222	dapA	APL_1222	APL_0899	Aspartate-semialdehyde dehydrogenase.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.630
APL_1222	lysC	APL_1222	APL_0710	Aspartate-semialdehyde dehydrogenase.	Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family.	0.759
APL_1222	thrA	APL_1222	APL_0250	Aspartate-semialdehyde dehydrogenase.	Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.	0.900
argD	dapA	APL_0244	APL_0899	Acetylornithine aminotransferase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.632
argD	dapD	APL_0244	APL_1861	Acetylornithine aminotransferase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.	0.918
argD	lysC	APL_0244	APL_0710	Acetylornithine aminotransferase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family.	0.594
argD	thrA	APL_0244	APL_0250	Acetylornithine aminotransferase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.	0.739
asd	dapA	APL_0005	APL_0899	Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.926
asd	lysC	APL_0005	APL_0710	Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family.	0.951
asd	thrA	APL_0005	APL_0250	Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.	0.980
dapA	APL_1222	APL_0899	APL_1222	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Aspartate-semialdehyde dehydrogenase.	0.630
dapA	argD	APL_0899	APL_0244	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Acetylornithine aminotransferase (ACOAT); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.	0.632
dapA	asd	APL_0899	APL_0005	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Aspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.926
dapA	dapB	APL_0899	APL_0684	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.	0.987
dapA	dapD	APL_0899	APL_1861	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.	0.687
dapA	dapF	APL_0899	APL_1531	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.	0.721
dapA	lysA	APL_0899	APL_1525	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.902
dapA	lysC	APL_0899	APL_0710	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family.	0.733
dapA	pheA	APL_0899	APL_1033	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	P-protein; Includes: Chorismate mutase; Prephenate dehydratase.	0.577
dapA	thrA	APL_0899	APL_0250	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.	0.967

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