Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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[Homology]
Score
metND-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (344 aa)    
Predicted Functional Partners:
metI
D-methionine transport system permease protein MetI.
 
 0.999
plpA
Outer membrane lipoprotein 1 precursor; Belongs to the nlpA lipoprotein family.
 
 0.995
plpB
Outer membrane lipoprotein 2 precursor; Belongs to the nlpA lipoprotein family.
 
 0.992
cydC
Transport ATP-binding protein CydC.
 
    
0.767
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.548
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.539
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.521
thrA
Bifunctional aspartokinase/homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.482
metJ
Transcriptional repressor protein MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
   
    0.414
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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