node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APL_0240 | cps5C | APL_0240 | APL_1579 | Tetratricopeptide repeat (TPR) family protein. | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | 0.717 |
APL_0240 | dnaJ | APL_0240 | APL_1905 | Tetratricopeptide repeat (TPR) family protein. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.585 |
APL_0240 | dnaK | APL_0240 | APL_1906 | Tetratricopeptide repeat (TPR) family protein. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.689 |
APL_0240 | hscA | APL_0240 | APL_0925 | Tetratricopeptide repeat (TPR) family protein. | Chaperone protein HscA-like protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.728 |
APL_0240 | htpG | APL_0240 | APL_0987 | Tetratricopeptide repeat (TPR) family protein. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.813 |
APL_0240 | ppiB | APL_0240 | APL_0914 | Tetratricopeptide repeat (TPR) family protein. | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.712 |
clpB | cps5C | APL_1087 | APL_1579 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | 0.472 |
clpB | dnaJ | APL_1087 | APL_1905 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.830 |
clpB | dnaK | APL_1087 | APL_1906 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.876 |
clpB | groEL | APL_1087 | APL_1012 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.827 |
clpB | grpE | APL_1087 | APL_0367 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Heat shock protein (HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several r [...] | 0.830 |
clpB | hscA | APL_1087 | APL_0925 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein HscA-like protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.876 |
clpB | htpG | APL_1087 | APL_0987 | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.796 |
cps5C | APL_0240 | APL_1579 | APL_0240 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Tetratricopeptide repeat (TPR) family protein. | 0.717 |
cps5C | clpB | APL_1579 | APL_1087 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.472 |
cps5C | dnaJ | APL_1579 | APL_1905 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.762 |
cps5C | dnaK | APL_1579 | APL_1906 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.778 |
cps5C | hscA | APL_1579 | APL_0925 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Chaperone protein HscA-like protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.778 |
cps5C | htpG | APL_1579 | APL_0987 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.877 |
cps5C | ppiB | APL_1579 | APL_0914 | Region 2 capsular polysaccharide biosynthesis protein; Pubmed:9632602. | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.491 |