Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
deoDPurine nucleoside phosphorylase DeoD-like protein. (240 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.965
nadR
Transcriptional regulator NadR.
    
 0.928
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
 0.919
ushA
UshA precursor; Includes: UDP-sugar hydrolase; 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.908
hpt
Yypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.907
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor; Belongs to the 5'-nucleotidase family.
    
 0.901
APL_1743
Ser/Thr protein phosphatase family protein; Belongs to the 5'-nucleotidase family.
    
 0.901
APL_0145
Hypothetical protein.
     
  0.900
APL_0313
Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Belongs to the dGTPase family. Type 2 subfamily.
     
  0.900
APL_0431
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
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