Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xylAXylose isomerase; Belongs to the xylose isomerase family. (439 aa)    
Predicted Functional Partners:
xylB
Xylulose kinase (Xylulokinase).
 
 
 0.987
fruA
PTS system fructose-specific EIIBC component; Includes: Fructose-specific phosphotransferase enzyme IIB component; Fructose permease IIC component.
     
 0.943
scrK
Fructokinase; Belongs to the carbohydrate kinase PfkB family.
     
 0.907
lacZ
Beta-galactosidase.
    
 0.814
xylF
D-xylose-binding periplasmic protein precursor.
 
  
 0.777
xylR
Xylose operon regulatory protein.
 
   
 0.776
xylH
Xylose transport system permease protein xylH; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.574
APL_0935
Aerobic respiration control sensor protein.
   
  
 0.481
galM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
 
  
 0.474
lyx
Putative L-xylulose kinase; Belongs to the FGGY kinase family.
 
  
 0.465
Your Current Organism:
Actinobacillus pleuropneumoniae
NCBI taxonomy Id: 416269
Other names: A. pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae L20, Actinobacillus pleuropneumoniae serovar 5b str. L20, Actinobacillus pleuropneumoniae serovar 5b strain L20
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.