Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
rbsDRbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (140 aa)    
Predicted Functional Partners:
rbsK
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 
 0.935
Tlet_0185
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: psb:Psyr_2570 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.916
Tlet_1325
Monosaccharide-transporting ATPase; PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: tma:TM0958 D-ribose transport system substrate-binding protein.
 
  
 0.912
Tlet_0182
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ctc:CTC00907 D-ribose-binding periplasmic protein.
 
  
 0.901
Tlet_0184
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rxy:Rxyl_3003 ABC transporter related.
  
  
 0.900
rbsK-2
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 
 0.784
Tlet_1328
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: tma:TM0955 D-ribose transport system permease protein.
 
  
 0.775
Tlet_0190
PFAM: aldo/keto reductase; KEGG: sfu:Sfum_1762 aldo/keto reductase.
       0.773
rbsK-3
PfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 
 0.758
Tlet_0183
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
     
 0.746
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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