STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0225PFAM: thioesterase superfamily protein; KEGG: tte:TTE0718 acyl-CoA hydrolase. (132 aa)    
Predicted Functional Partners:
Tlet_0226
PFAM: protein of unknown function DUF849; KEGG: fnu:FN1868 hypothetical cytosolic protein.
  
 0.999
Tlet_1713
PFAM: cobalamin B12-binding domain protein; KEGG: sth:STH38 lysine 5,6-aminomutase beta subunit.
 
   
 0.849
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.848
Tlet_1712
PFAM: D-Lysine 56-aminomutase alpha subunit; KEGG: tte:TTE0726 D-lysine 5,6-aminomutase alpha subunit.
 
  
 0.842
Tlet_1664
PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: tte:TTE0722 hypothetical protein.
 
   
 0.831
Tlet_0487
KEGG: pgi:PG1071 hypothetical protein.
 
     0.805
Tlet_0224
PFAM: protein of unknown function DUF6 transmembrane; KEGG: tma:TM0586 hypothetical protein.
     
 0.780
Tlet_0223
PFAM: protein of unknown function DUF342; KEGG: csc:Csac_1286 protein of unknown function DUF342.
       0.539
Tlet_0488
TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: ctc:CTC00890 L-lysine 2,3-aminomutase.
 
   
 0.461
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
  
 0.403
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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