Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
acpS2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (268 aa)    
Predicted Functional Partners:
Tlet_0902
TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; KEGG: tma:TM0040 dihydropteroate synthase.
 
 0.999
Tlet_1984
TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: tma:TM0166 folylpolyglutamate synthase / dihydrofolate synthase.
  
 0.954
Tlet_0141
PFAM: Alkaline phosphatase; KEGG: tma:TM0156 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.904
Tlet_1583
PFAM: Alkaline phosphatase; KEGG: tma:TM0156 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.904
Tlet_1322
PFAM: beta-lactamase domain protein; KEGG: tma:TM1679 hypothetical protein.
    
  0.902
Tlet_0266
Conserved carboxylase region; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: tma:TM0128 oxaloacetate decarboxylase, alpha subunit.
       0.846
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.831
acpP-2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.831
Tlet_0264
Hypothetical protein.
       0.816
Tlet_0267
PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: tma:TM0129 carboxypeptidase G2, putative.
  
  
 0.804
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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