STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0331PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: tte:TTE1591 threonine dehydrogenase and related Zn-dependent dehydrogenase. (314 aa)    
Predicted Functional Partners:
Tlet_0330
PFAM: PfkB domain protein; KEGG: tma:TM0795 sugar kinase, PfkB family.
  
  
 0.794
Tlet_0325
PFAM: Polyprenyl synthetase; KEGG: tma:TM0161 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.662
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
       0.625
Tlet_0328
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: smr:Smar_0789 UBA/ThiF-type NAD/FAD binding protein.
     
 0.563
Tlet_0329
Hypothetical protein.
       0.562
Tlet_0327
TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: tma:TM1693 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
  
    0.554
Tlet_0324
KEGG: tma:TM0162 hypothetical protein.
  
    0.551
Tlet_0323
PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: tma:TM0163 hypothetical protein.
       0.537
Tlet_0326
PFAM: protein of unknown function DUF151; KEGG: tma:TM0160 hypothetical protein.
       0.537
Tlet_1880
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: tma:TM0436 alcohol dehydrogenase, zinc-containing.
 
 
0.520
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.