Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tlet_0387PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: tma:TM1816 hypothetical protein. (142 aa)    
Predicted Functional Partners:
Tlet_0386
PFAM: transcriptional regulator PadR family protein; KEGG: mta:Moth_2210 transcriptional regulator, PadR-like family.
 
     0.818
Tlet_1520
NADH dehydrogenase (quinone); PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: tma:TM0010 NADH dehydrogenase I chain F.
  
  
 0.571
Tlet_0262
2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; KEGG: dsy:DSY0970 hypothetical protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 0.436
Tlet_0066
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: tma:TM0912 basic membrane protein, putative.
  
  
 0.422
Tlet_0388
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: tte:TTE1948 sugar phosphate isomerase/epimerase.
       0.408
Tlet_0383
PFAM: response regulator receiver; KEGG: tma:TM1360 response regulator.
  
  
 0.400
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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