STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0442Hypothetical protein. (406 aa)    
Predicted Functional Partners:
Tlet_0438
PFAM: protein of unknown function DUF1312; KEGG: tma:TM1554 hypothetical protein.
       0.800
Tlet_0439
PFAM: Heptaprenyl diphosphate synthase component I; KEGG: tma:TM1555 hypothetical protein.
       0.800
Tlet_0440
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.800
Tlet_0441
PFAM: helix-hairpin-helix motif; DNA repair protein RadC; KEGG: tma:TM1557 DNA repair protein; Belongs to the UPF0758 family.
       0.800
Tlet_0436
PFAM: Radical SAM domain protein; KEGG: tma:TM1552 pyruvate formate-lyase activating enzyme.
       0.795
Tlet_0437
ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
       0.795
Tlet_0443
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tma:TM1558 hypothetical protein.
       0.792
Tlet_0435
PFAM: AMMECR1 domain protein; KEGG: tma:TM1551 hypothetical protein.
       0.773
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
       0.771
Tlet_0445
PFAM: Formiminotransferase-cyclodeaminase; KEGG: tma:TM1560 serine cycle enzyme, putative.
       0.757
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.