STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0493PFAM: iron-containing alcohol dehydrogenase; KEGG: tma:TM0920 alcohol dehydrogenase, iron-containing. (362 aa)    
Predicted Functional Partners:
Tlet_0494
KEGG: tma:TM1697 hypothetical protein.
       0.806
Tlet_1880
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: tma:TM0436 alcohol dehydrogenase, zinc-containing.
  
 
 0.783
Tlet_0491
TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: tma:TM1866 membrane bound protein LytR, putative.
     
 0.773
nfi
Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.760
Tlet_0495
PFAM: aminotransferase class I and II; KEGG: tma:TM1698 aspartate aminotransferase.
  
  
 0.758
murJ
Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
       0.746
Tlet_0192
PFAM: aldehyde dehydrogenase; KEGG: mtp:Mthe_0395 betaine-aldehyde dehydrogenase.
 
 
 0.633
glgA
Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.575
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.567
Tlet_0488
TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: ctc:CTC00890 L-lysine 2,3-aminomutase.
     
 0.547
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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