STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0573PFAM: carbon starvation protein CstA; KEGG: aae:aq_1265 carbon starvation protein A. (573 aa)    
Predicted Functional Partners:
Tlet_0261
PFAM: Na+ symporter; KEGG: rxy:Rxyl_2906 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.771
Tlet_0571
Signal transduction histidine kinase, LytS; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: chy:CHY_2219 sensor histidine kinase.
 
   
 0.714
Tlet_0572
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: btl:BALH_4946 response regulator.
 
   
 0.670
Tlet_0192
PFAM: aldehyde dehydrogenase; KEGG: mtp:Mthe_0395 betaine-aldehyde dehydrogenase.
   
    0.517
Tlet_1448
TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: ape:APE_0807.1 delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
    0.517
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.476
rbsD
RbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
   
    0.443
Tlet_0570
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM1164 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
    0.437
Tlet_0569
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: pfu:PF0753 2-oxoglutarate ferredoxin oxidoreductase, beta subunit.
  
    0.408
rpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
       0.405
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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