STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0630PFAM: CheW domain protein; KEGG: tma:TM0701 purine-binding chemotaxis protein. (153 aa)    
Predicted Functional Partners:
Tlet_0631
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: tma:TM0702 chemotaxis sensor histidine kinase CheA.
 
 0.999
Tlet_0138
PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: tma:TM0918 methyl-accepting chemotaxis protein.
 
 0.995
Tlet_1737
PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: tma:TM0429 methyl-accepting chemotaxis protein.
 
 0.995
Tlet_1846
PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: tma:TM0429 methyl-accepting chemotaxis protein.
 
 0.995
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.994
Tlet_0651
PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: tma:TM0429 methyl-accepting chemotaxis protein.
 
 0.992
Tlet_1826
TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: tte:TTE1429 chemotaxis protein CheC, inhibitor of MCP methylation.
  
  
 0.989
Tlet_0629
PFAM: response regulator receiver; KEGG: tma:TM0700 chemotaxis response regulator CheY.
 
 
 0.987
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.963
Tlet_0858
PFAM: chemotaxis sensory transducer; KEGG: bha:BH3915 methyl-accepting chemotaxis protein.
 
 
 0.927
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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