STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0703TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aae:aq_035 hypothetical protein. (535 aa)    
Predicted Functional Partners:
Tlet_1224
PFAM: EAL domain protein; KEGG: dde:Dde_1073 diguanylate phosphodiesterase (EAL domain).
  
 0.992
Tlet_0700
PFAM: helix-turn-helix Fis-type; KEGG: tma:TM1580 transcriptional regulator, putative.
  
  
 0.826
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: tma:TM0168 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
   0.799
Tlet_0701
PFAM: phosphate acetyl/butaryl transferase; KEGG: bcz:BCZK3918 phosphate acetyltransferase.
     
 0.785
Tlet_0702
PFAM: peptidase M55 D-aminopeptidase; KEGG: efa:EF2723 putative peptide transport protein.
       0.773
Tlet_0027
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: shm:Shewmr7_3231 response regulator receiver modulated metal dependent phosphohydrolase.
 
 0.768
Tlet_1743
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tma:TM1467 hypothetical protein.
 
 0.765
Tlet_0194
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbl:Sbal_3086 metal dependent phosphohydrolase.
 
 0.759
Tlet_1338
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: extracellular solute-binding protein family 3; metal-dependent phosphohydrolase HD region; KEGG: tma:TM1170 ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein.
 
 0.695
Tlet_0806
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tte:TTE0518 HD-GYP domain.
 
 0.689
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: low (30%) [HD]