node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tlet_0766 | cysS | Tlet_0766 | Tlet_0764 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; KEGG: tma:TM1821 8-oxoguanine DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.772 |
Tlet_0766 | gltX1 | Tlet_0766 | Tlet_0765 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; KEGG: tma:TM1821 8-oxoguanine DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.772 |
Tlet_0766 | glyA | Tlet_0766 | Tlet_0763 | DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; KEGG: tma:TM1821 8-oxoguanine DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.772 |
Tlet_0973 | Tlet_0974 | Tlet_0973 | Tlet_0974 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tma:TM0665 cysteine synthase. | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. | 0.999 |
Tlet_0973 | cysS | Tlet_0973 | Tlet_0764 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tma:TM0665 cysteine synthase. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.933 |
Tlet_0974 | Tlet_0973 | Tlet_0974 | Tlet_0973 | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tma:TM0665 cysteine synthase. | 0.999 |
Tlet_0974 | cysS | Tlet_0974 | Tlet_0764 | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.983 |
Tlet_0974 | glyA | Tlet_0974 | Tlet_0763 | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.840 |
Tlet_0974 | mrnC | Tlet_0974 | Tlet_1480 | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. | Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.440 |
Tlet_1481 | cysS | Tlet_1481 | Tlet_0764 | TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: tma:TM1741 putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.787 |
Tlet_1481 | leuS | Tlet_1481 | Tlet_1847 | TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: tma:TM1741 putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | TIGRFAM: leucyl-tRNA synthetase; KEGG: tma:TM0168 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.477 |
Tlet_1481 | mrnC | Tlet_1481 | Tlet_1480 | TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: tma:TM1741 putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.922 |
cysS | Tlet_0766 | Tlet_0764 | Tlet_0766 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-(apurinic or apyrimidinic site) lyase; PFAM: HhH-GPD family protein; KEGG: tma:TM1821 8-oxoguanine DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase. | 0.772 |
cysS | Tlet_0973 | Tlet_0764 | Tlet_0973 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tma:TM0665 cysteine synthase. | 0.933 |
cysS | Tlet_0974 | Tlet_0764 | Tlet_0974 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: serine O-acetyltransferase; KEGG: tma:TM0666 serine acetyltransferase. | 0.983 |
cysS | Tlet_1481 | Tlet_0764 | Tlet_1481 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: tma:TM1741 putative tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.787 |
cysS | gltX1 | Tlet_0764 | Tlet_0765 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.849 |
cysS | glyA | Tlet_0764 | Tlet_0763 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.865 |
cysS | leuS | Tlet_0764 | Tlet_1847 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: leucyl-tRNA synthetase; KEGG: tma:TM0168 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.718 |
cysS | mrnC | Tlet_0764 | Tlet_1480 | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: tma:TM0719 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.837 |