Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tlet_0769PFAM: sugar isomerase (SIS); KEGG: pab:PAB2201 glucosamine--fructose-6-phosphate aminotransferase. (335 aa)    
Predicted Functional Partners:
Tlet_0542
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
 
 
  0.930
Tlet_1990
TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: tpe:Tpen_1093 N-acetylglucosamine-6-phosphate deacetylase.
  
 
 0.926
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
  0.911
Tlet_0682
PFAM: mannose-6-phosphate isomerase type I; KEGG: tma:TM0736 mannose-6-phosphate isomerase.
    
  0.907
Tlet_0193
PFAM: glucose-6-phosphate isomerase; KEGG: pab:PAB1199 glucose-6-phosphate isomerase.
   
 
  0.903
Tlet_0896
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: tma:TM0943 glutamine synthetase.
     
 0.903
Tlet_2058
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: swo:Swol_1787 glutamate--ammonia ligase.
     
 0.903
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: tma:TM1385 glucose-6-phosphate isomerase; Belongs to the GPI family.
    
  0.901
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: tma:TM0558 carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
     
  0.900
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: tma:TM0557 carbamoyl-phosphate synthase large chain.
     
  0.900
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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