Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Tlet_0806TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tte:TTE0518 HD-GYP domain. (503 aa)    
Predicted Functional Partners:
Tlet_1255
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tdn:Tmden_1336 diguanylate cyclase (GGDEF domain).
 
   0.944
Tlet_0805
Hypothetical protein.
       0.829
Tlet_0804
TIGRFAM: degV family protein; PFAM: DegV family protein; KEGG: tma:TM1468 hypothetical protein.
       0.786
Tlet_1870
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rme:Rmet_6140 diguanylate cyclase/phosphodiesterase (GGDEF and EAL domains) with PAS/PAC sensor(s).
 
   0.746
Tlet_0703
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aae:aq_035 hypothetical protein.
 
 0.679
Tlet_1736
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cno:NT01CX_2392 diguanylate cyclase/phosphodiesterase domain 2.
 
   0.644
Tlet_1963
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein.
 
 0.638
Tlet_0424
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein.
 
 
 0.587
Tlet_0800
PFAM: inner-membrane translocator; KEGG: tma:TM1136 branched-chain amino acid transport system permease protein.
       0.539
Tlet_0801
PFAM: inner-membrane translocator; KEGG: tma:TM1137 branched-chain amino acid transport system permease protein.
       0.539
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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