STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0824PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rxy:Rxyl_0080 short-chain dehydrogenase/reductase SDR. (274 aa)    
Predicted Functional Partners:
Tlet_0823
KEGG: tma:TM0442 hypothetical protein.
 
     0.847
Tlet_0825
KEGG: tma:TM0440 hypothetical protein.
 
     0.817
Tlet_1289
PFAM: Glucuronate isomerase; KEGG: tma:TM0064 uronate isomerase, putative.
 
  
 0.756
Tlet_0826
Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; regulatory protein DeoR; KEGG: tte:TTE2588 Transcriptional regulator of sugar metabolism.
     
 0.746
Tlet_1557
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: fnu:FN0495 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.655
Tlet_0135
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ava:Ava_1011 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.642
Tlet_0414
TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: tma:TM1635 exonuclease, putative.
   
 
 0.640
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.558
Tlet_0430
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: tma:TM0798 malonyl CoA-acyl carrier protein transacylase.
  
 
 0.502
Tlet_1831
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: tte:TTE0545 Acyl-CoA dehydrogenases.
 
 0.455
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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