STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0847TIGRFAM: metal dependent phophohydrolase; PFAM: extracellular solute-binding protein family 3; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tma:TM1170 ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein. (677 aa)    
Predicted Functional Partners:
Tlet_1255
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tdn:Tmden_1336 diguanylate cyclase (GGDEF domain).
 
 0.897
Tlet_0848
Hypothetical protein.
       0.773
Tlet_1963
TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein.
 
 0.665
Tlet_1826
TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: tte:TTE1429 chemotaxis protein CheC, inhibitor of MCP methylation.
  
 
 0.605
Tlet_0703
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aae:aq_035 hypothetical protein.
 
 0.600
Tlet_1870
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rme:Rmet_6140 diguanylate cyclase/phosphodiesterase (GGDEF and EAL domains) with PAS/PAC sensor(s).
 
 0.571
Tlet_0424
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein.
 
 
 0.562
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
       0.559
Tlet_1224
PFAM: EAL domain protein; KEGG: dde:Dde_1073 diguanylate phosphodiesterase (EAL domain).
 
  
 0.555
Tlet_0384
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: tma:TM1359 sensor histidine kinase.
     
 0.538
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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