STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0892PFAM: cation transporter; KEGG: tma:TM1089 TRK system potassium uptake protein TrkH. (496 aa)    
Predicted Functional Partners:
Tlet_0893
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: tma:TM1088 trk system potassium uptake protein TrkA.
 
 
 0.989
Tlet_0894
PFAM: TrkA-N domain protein; KEGG: mta:Moth_1348 TrkA.
 
 
 0.989
Tlet_0896
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: tma:TM0943 glutamine synthetase.
     
 0.870
Tlet_0431
Chloride channel core; PFAM: TrkA-C domain protein; Chloride channel core; KEGG: cno:NT01CX_0195 voltage gated chloride channel family protein.
  
 
 0.867
Tlet_0895
PFAM: response regulator receiver; Tetratricopeptide TPR_2 repeat protein; KEGG: gme:Gmet_0010 multi-sensor signal transduction histidine kinase.
       0.829
Tlet_0118
PFAM: TrkA-N domain protein; TrkA-C domain protein; Ion transport 2 domain protein; KEGG: tma:TM1057 potassium channel, putative.
  
 
 0.770
Tlet_0263
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: tma:TM1015 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.627
Tlet_0898
D-alanine--D-alanine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein; KEGG: ade:Adeh_2449 D-alanine--D-alanine ligase.
  
    0.496
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.487
Tlet_0899
PFAM: cobalamin B12-binding domain protein; KEGG: tte:TTE0924 methionine synthase I, cobalamin-binding domain.
       0.471
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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