STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
mtaDAmidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (413 aa)    
Predicted Functional Partners:
Tlet_0879
TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: tma:TM0172 adenosylhomocysteinase.
 
 
 0.949
Tlet_0708
PFAM: purine or other phosphorylase family 1; KEGG: tma:TM1129 5-methylthioadenosine / S-adenosylhomocysteine nucleosidase.
    
 0.919
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
   
 0.913
Tlet_0939
TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tma:TM0515 hypothetical protein.
 
     0.844
Tlet_0936
SMC domain protein; May be involved in recombinational repair of damaged DNA.
       0.790
Tlet_0937
PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: tma:TM0769 phosphomannomutase.
  
    0.789
Tlet_0935
PFAM: UvrD/REP helicase; KEGG: tma:TM1238 ATP-dependent DNA helicase.
   
 
 0.766
Tlet_1602
PFAM: band 7 protein; KEGG: tma:TM0866 hypothetical protein.
      0.677
Tlet_0136
TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate transcarbamylase regulatory subunit; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: tma:TM1642 aspartate carbamoyltransferase, catalytic and regulatory chains.
  
  
 0.648
Tlet_0934
Hypothetical protein.
       0.624
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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