Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_0955PFAM: Stage II sporulation E family protein; KEGG: tma:TM1423 hypothetical protein. (379 aa)    
Predicted Functional Partners:
Tlet_0956
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; KEGG: tte:TTE0697 ferredoxin 2.
 
     0.959
Tlet_0957
NADH:ubiquinone oxidoreductase 24 kD subunit-like protein; KEGG: tma:TM1420 hypothetical protein.
 
     0.959
Tlet_0952
Hydrogenase large subunit domain protein; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; hydrogenase large subunit domain protein; KEGG: tma:TM1426 NADH dehydrogenase I chain G.
 
    0.830
Tlet_1635
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; ATP-binding region ATPase domain protein; KEGG: tma:TM1354 inosine-5-monophosphate dehydrogenase-related protein.
 
 
 0.830
Tlet_0953
NADH dehydrogenase (quinone); PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: tma:TM1425 NADH dehydrogenase I chain F.
       0.821
Tlet_0954
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: tma:TM1424 NADH dehydrogenase I chain E.
       0.806
rex-2
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
     
 0.804
Tlet_1748
PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: tma:TM1267 thiH protein, putative.
  
    0.788
Tlet_0950
PFAM: protein of unknown function DUF1232; KEGG: sfu:Sfum_3856 protein of unknown function DUF1232.
       0.746
Tlet_0685
Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: tma:TM0733 sigma-B regulator, putative.
  
 
 0.724
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.