STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1027PFAM: fumarate lyase; KEGG: tma:TM0444 aspartate ammonia-lyase. (457 aa)    
Predicted Functional Partners:
Tlet_0908
TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: bca:BCE_0308 aspartate racemase.
   
 0.945
Tlet_1732
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: tma:TM1095 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.912
Tlet_0297
PFAM: aminotransferase class I and II; KEGG: tma:TM1255 aspartate aminotransferase.
    
 0.910
Tlet_0364
PFAM: fumarate lyase; KEGG: tma:TM1781 argininosuccinate lyase.
     
 0.910
Tlet_0495
PFAM: aminotransferase class I and II; KEGG: tma:TM1698 aspartate aminotransferase.
    
 0.910
Tlet_1113
PFAM: fumarate lyase; KEGG: atc:AGR_L_463 argininosuccinate lyase (arginosuccinase) (ASAL); Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
     
 0.910
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.910
Tlet_0136
TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate transcarbamylase regulatory subunit; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: tma:TM1642 aspartate carbamoyltransferase, catalytic and regulatory chains.
     
  0.900
Tlet_1026
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: tma:TM0445 hypothetical protein.
 
  
 0.871
Tlet_0570
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tma:TM1164 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
   
 0.838
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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