STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_10693-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)    
Predicted Functional Partners:
Tlet_0430
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: tma:TM0798 malonyl CoA-acyl carrier protein transacylase.
 0.988
Tlet_1067
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: tte:TTE0553 3-oxoacyl-(acyl carrier protein) synthase.
 
 
 0.981
Tlet_1075
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: mxa:MXAN_0215 putative 3-oxoacyl-(acyl-carrier-protein) synthase.
 
 
 0.980
Tlet_0427
Beta-ketoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.977
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.950
Tlet_1070
PFAM: Extracellular ligand-binding receptor; KEGG: sth:STH803 putative branched chain amino acid ABC transporter substrate-binding protein.
   
 
 0.754
Tlet_1068
PFAM: acetyl-CoA hydrolase/transferase; KEGG: tte:TTE0554 acetyl-CoA hydrolase.
  
   0.751
Tlet_1074
Inner-membrane translocator; PFAM: alpha/beta hydrolase fold domain-containing protein; inner-membrane translocator; KEGG: det:DET0944 high-affinity branched-chain amino acid ABC transporter, permease protein, putative; Belongs to the binding-protein-dependent transport system permease family.
  
 0.727
Tlet_1076
PFAM: alpha/beta hydrolase fold domain-containing protein; KEGG: chy:CHY_1729 hydrolase, alpha/beta fold family.
  
 0.682
Tlet_1557
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: fnu:FN0495 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.659
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.