STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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Textmining
[Homology]
Score
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (382 aa)    
Predicted Functional Partners:
Tlet_0731
TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: tma:TM1518 aspartokinase II; Belongs to the aspartokinase family.
  
 0.966
Tlet_1364
TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: mka:MK0109 aspartokinase; Belongs to the aspartokinase family.
  
 0.957
Tlet_1949
PFAM: diaminopimelate epimerase; KEGG: tma:TM1522 diaminopimelate epimerase; Belongs to the diaminopimelate epimerase family.
 
 0.950
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
     
 0.913
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
 0.828
Tlet_0488
TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: ctc:CTC00890 L-lysine 2,3-aminomutase.
     
 0.809
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
   
 0.780
Tlet_1266
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bxe:Bxe_C1111 ABC transporter, ATPase subunit.
       0.762
Tlet_1267
PFAM: inner-membrane translocator; KEGG: swo:Swol_0324 hypothetical protein; Belongs to the binding-protein-dependent transport system permease family.
       0.762
Tlet_1268
PFAM: protein of unknown function DUF534; KEGG: hch:HCH_04501 ABC-type uncharacterized transport system, periplasmic component.
       0.762
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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