STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1345PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tpe:Tpen_1816 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (142 aa)    
Predicted Functional Partners:
Tlet_1346
PFAM: Aldehyde ferredoxin oxidoreductase; KEGG: mtp:Mthe_0900 aldehyde ferredoxin oxidoreductase.
 
 
 0.989
Tlet_0469
PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: pab:PAB0798 formaldehyde:ferredoxin oxidoreductase.
 
 
 0.944
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.897
Tlet_0952
Hydrogenase large subunit domain protein; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; hydrogenase large subunit domain protein; KEGG: tma:TM1426 NADH dehydrogenase I chain G.
  
  
 0.820
Tlet_1350
TIGRFAM: hydrogenase, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; hydrogenase large subunit domain protein; KEGG: tma:TM0201 NADH dehydrogenase I chain G.
  
  
 0.820
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.790
Tlet_1342
PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: cpe:CPE1270 probable ABC transporter; Belongs to the ABC transporter superfamily.
     
 0.711
Tlet_1343
PFAM: purine or other phosphorylase family 1; KEGG: tko:TK1479 uridine phosphorylase.
       0.668
ade
Adenine deaminase; PFAM: amidohydrolase; KEGG: cpe:CPE1268 probable adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.668
Tlet_1339
PFAM: extracellular solute-binding protein family 1; KEGG: sme:SMb21273 putative spermidineputrescine ABC transporter periplasmic solute-binding protein precursor.
       0.658
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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