STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1375PFAM: MscS Mechanosensitive ion channel; KEGG: tma:TM1563 hypothetical protein. (260 aa)    
Predicted Functional Partners:
Tlet_1373
PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; KEGG: tma:TM0495 PhoH-related protein.
  
    0.797
Tlet_1374
TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: tma:TM0496 DNA polymerase III, epsilon subunit.
       0.789
Tlet_1372
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tma:TM0793 putative ABC-2 type transport system ATP-binding protein.
  
    0.758
Tlet_1371
Hypothetical protein; KEGG: tma:TM0794 putative ABC-2 type transport system permease protein.
       0.757
Tlet_1369
PFAM: protein of unknown function DUF81; KEGG: tma:TM0376 hypothetical protein.
  
    0.614
Tlet_1370
PFAM: peptidase M20; peptidase M42 family protein; KEGG: pho:PH0519 thermostable aminopeptidase.
       0.605
Tlet_1380
TIGRFAM: cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; KEGG: tma:TM0857 riboflavin kinase / FMN adenylyltransferase.
  
    0.600
Tlet_1376
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: tma:TM0853 sensor histidine kinase.
     
 0.562
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.552
Tlet_1377
PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; KEGG: tma:TM0854 hypothetical protein.
  
    0.550
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.