STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1403PFAM: peptidase M16 domain protein; KEGG: tma:TM1346 processing protease. (408 aa)    
Predicted Functional Partners:
Tlet_1520
NADH dehydrogenase (quinone); PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: tma:TM0010 NADH dehydrogenase I chain F.
  
 
 0.999
Tlet_0878
Protein of unknown function DUF362; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF362; KEGG: tma:TM0049 iron-sulfur cluster-binding protein.
  
 
 0.899
Tlet_0953
NADH dehydrogenase (quinone); PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: tma:TM1425 NADH dehydrogenase I chain F.
   
 
 0.890
Tlet_1518
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: tma:TM0228 NADH dehydrogenase I chain F.
   
 
 0.890
Tlet_0954
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: tma:TM1424 NADH dehydrogenase I chain E.
   
 
 0.852
Tlet_0957
NADH:ubiquinone oxidoreductase 24 kD subunit-like protein; KEGG: tma:TM1420 hypothetical protein.
   
 
 0.852
Tlet_1519
TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: sat:SYN_00153 NADH:ubiquinone oxidoreductase 24 kD subunit NuoE.
   
 
 0.852
Tlet_1522
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: tma:TM0012 NADH dehydrogenase I chain E.
   
 
 0.852
atpH
ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
   
 
 0.827
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.816
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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