Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Tlet_1600PFAM: beta-lactamase domain protein; KEGG: tma:TM0864 hypothetical protein. (278 aa)    
Predicted Functional Partners:
rplI
Ribosomal protein L9; Binds to the 23S rRNA.
   
   0.839
Tlet_1602
PFAM: band 7 protein; KEGG: tma:TM0866 hypothetical protein.
  
   0.819
Tlet_1601
PFAM: protein of unknown function DUF107; KEGG: tma:TM0865 hypothetical protein.
       0.809
Tlet_1603
KEGG: tma:TM0867 hypothetical protein.
       0.755
Tlet_1605
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: tma:TM0869 thioredoxin reductase.
  
    0.676
Tlet_1604
TIGRFAM: glutaredoxin-like domain protein; PFAM: glutaredoxin; KEGG: tma:TM0868 glutaredoxin-related protein.
       0.675
Tlet_1714
PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; KEGG: tma:TM0715 tRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.641
Tlet_1597
TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; KEGG: tma:TM0171 hypothetical protein.
 
     0.628
Tlet_0774
PFAM: O-antigen polymerase; KEGG: tma:TM0806 hypothetical protein.
 
     0.622
Tlet_1596
PFAM: GTP-binding protein HSR1-related; KEGG: tma:TM0848 hypothetical protein.
 
    0.609
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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