STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1639PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: tte:TTE2368 6-pyruvoyltetrahydropterin synthase. (118 aa)    
Predicted Functional Partners:
folE2
Protein of unknown function DUF198; Converts GTP to 7,8-dihydroneopterin triphosphate.
 
  
 0.988
Tlet_0141
PFAM: Alkaline phosphatase; KEGG: tma:TM0156 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Tlet_1357
Putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein Crp; KEGG: ctc:CTC01969 transcriptional regulatory protein.
    
  0.900
Tlet_1583
PFAM: Alkaline phosphatase; KEGG: tma:TM0156 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Tlet_1635
Putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; ATP-binding region ATPase domain protein; KEGG: tma:TM1354 inosine-5-monophosphate dehydrogenase-related protein.
       0.838
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
       0.794
Tlet_1632
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: tma:TM1665 hypothetical protein.
  
    0.791
Tlet_1641
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bld:BLi02688 putative ABC transporter (ATP-binding protein); RBL03928.
       0.790
Tlet_1633
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: tma:TM1352 hypothetical protein.
       0.789
Tlet_1634
KEGG: tma:TM1353 hypothetical protein.
       0.789
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.