STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1663PFAM: extracellular solute-binding protein family 1; KEGG: tma:TM0595 multiple sugar transport system substrate-binding protein. (419 aa)    
Predicted Functional Partners:
Tlet_0778
Monosaccharide-transporting ATPase; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tma:TM0598 multiple sugar transport system permease protein.
 
   0.844
Tlet_1591
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tma:TM1122 putative sn-glycerol-3-phosphate transport system permease protein.
   0.822
Tlet_1590
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tma:TM1121 putative sn-glycerol-3-phosphate transport system permease protein.
 
   0.820
Tlet_0777
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tma:TM0596 multiple sugar transport system permease protein.
 
   0.814
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.785
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: tma:TM1385 glucose-6-phosphate isomerase; Belongs to the GPI family.
       0.783
Tlet_1661
Hypothetical protein.
       0.774
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.755
Tlet_1116
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: atc:AGR_L_458 sugar ABC transporter, permease protein.
  
   0.731
Tlet_0215
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lin:lin0219 similar to sugar ABC transporter, permease protein.
 
   0.692
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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