STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1823PFAM: OmpA/MotB domain protein; KEGG: tma:TM0677 motility protein B. (289 aa)    
Predicted Functional Partners:
Tlet_1822
PFAM: MotA/TolQ/ExbB proton channel; KEGG: tma:TM0676 motility protein A.
 
 0.999
Tlet_1826
TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: tte:TTE1429 chemotaxis protein CheC, inhibitor of MCP methylation.
 
  
 0.980
Tlet_1825
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: tma:TM0679 flagellar motor switch protein FliM.
 
  
 0.977
Tlet_0672
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; KEGG: tma:TM0083 flagellar hook-associated protein 1.
 
  
 0.971
Tlet_1824
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
 
 0.968
Tlet_1994
PFAM: flagellar protein FliS; KEGG: tma:TM1179 flagellar protein FliS.
 
  
 0.963
Tlet_0171
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.959
Tlet_1819
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.956
Tlet_1820
PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: tdn:Tmden_0032 flagellar hook FlgE.
 
 
 0.953
Tlet_0631
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: tma:TM0702 chemotaxis sensor histidine kinase CheA.
  
  
 0.944
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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