STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Tlet_1963TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: ttj:TTHA0989 GGDEF domain protein. (466 aa)    
Predicted Functional Partners:
Tlet_1224
PFAM: EAL domain protein; KEGG: dde:Dde_1073 diguanylate phosphodiesterase (EAL domain).
  
 0.992
Tlet_1987
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tma:TM0739 hypothetical protein.
 
 0.940
Tlet_1743
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: tma:TM1467 hypothetical protein.
 
 0.902
Tlet_1013
Protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; Methyltransferase type 11; KEGG: tma:TM0464 putative chemotaxis protein methyltransferase.
    
 0.827
Tlet_1338
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: extracellular solute-binding protein family 3; metal-dependent phosphohydrolase HD region; KEGG: tma:TM1170 ABC transporter, periplasmic substrate-binding protein/conserved hypothetical protein.
 
 0.804
Tlet_1962
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: tma:TM0208 pyruvate kinase; Belongs to the pyruvate kinase family.
       0.757
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.746
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: tma:TM0168 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.741
Tlet_0027
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: shm:Shewmr7_3231 response regulator receiver modulated metal dependent phosphohydrolase.
 
 0.737
Tlet_0194
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbl:Sbal_3086 metal dependent phosphohydrolase.
 
 0.709
Your Current Organism:
Pseudothermotoga lettingae
NCBI taxonomy Id: 416591
Other names: P. lettingae TMO, Pseudothermotoga lettingae TMO, Pseudothermotoga lettingae str. TMO, Pseudothermotoga lettingae strain TMO, Thermotoga lettingae TMO, Thermotoga sp. TMO
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